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KMID : 1059519970410080406
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Journal of the Korean Chemical Society
1997 Volume.41 No. 8 p.406 ~ p.413
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Evaluation of Endogeneous Steroids Profile after Administration of Anabolic Steroids
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Lee Seon-Hwa
Choi Man-Ho
Kim Tae-Wook
Chung Bong-Chul
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Abstract
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The endogenous steroids from human urine were simultaneously analyzed by selected ion monitoring method of GC/MS which is currently used for the doping procedure, together with anabolic steroids. The recovery range of this method was 72.33 %∼94.54% and the RSD values of precision and accuracy test were 1.43%∼10.86%, 0.96%∼9.98%, respectively. Using this method steroids profile was investigated in the urine of male volunteers after oral administration of nine anabolic steroids banned by IOC (International Olympic Committee). Urinary endogenous steroids level was varied specifically according to the excretion tendency of the metabolites of anabolic steroids.
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